Group I (mGlu5, mGlu1)
Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
MCC950 sodium salt (HB4636)
Description:Potent, selective NLRP3 inflammasome inhibitor
Purity:>98%
-
-
-
(S)-MCPG sodium salt (HB6112)
Description:Non-selective group I and II mGluR antagonist. Water soluble sodium salt.
Purity:>99%
-
(R,S)-MCPG sodium salt (HB0038)
Description:Water soluble, non-selective group I and II mGluR antagonist
Purity:>98%
-
-
- Description:
Inhibits α-MSH release inhibitors. Also increase dopamine levels.
