Group I (mGlu5, mGlu1)

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Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.

Items 611-620 of 1076

Set Descending Direction
  1. MHY 1485 (HB7154)

    Description:

    mTOR activator and autophagy inhibitor. Cell-permeable.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $58
    Qty:
    Pack:
    50mg
    Price:
    $182
    Qty:
  2. Description:

    Non-selective 5-HT2 receptor antagonist. Shows activity at other receptors.

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $97
    Qty:
  3. Pack:
    5mg
    Price:
    $113
    Qty:
    Pack:
    10mg
    Price:
    $201
    Qty:
    Pack:
    25mg
    Price:
    $474
    Qty:
  4. Mifepristone (HB2783)

    Description:

    Potent glucocorticoid and progesterone receptor antagonist. Also used for gene editing as a mifepristone inducible Cas9 and Cpf1 CRISPR effector.

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $85
    Qty:
  5. Description:

    5-HT and norepinephrine re-uptake inhibitor (SNRI)

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $122
    Qty:
    Pack:
    50mg
    Price:
    $432
    Qty:
  6. Pack:
    25mg
    Price:
    $87
    Qty:
    Pack:
    50mg
    Price:
    $132
    Qty:
    Pack:
    100mg
    Price:
    $197
    Qty:
    Pack:
    500mg
    Price:
    $783
    Qty:
  7. Minoxidil (HB1094)

    Description:

    Kir6 channel activator

    Purity:

    >99%

    Pack:
    500mg
    Price:
    $538
    Qty:
  8. Description:

    Highly selective, pan-Akt inhibitor. Autophagy and apoptosis inducer. Orally bioavailable.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $77
    Qty:
    Pack:
    50mg
    Price:
    $325
    Qty:
    Pack:
    10mM solution (in 1mL DMSO)
    Price:
    $125
    Qty:
  9. Description:

    Selective leukotriene LTD4 receptor antagonist. Potent MRP1 inhibitor.

    Purity:

    >97%

    Pack:
    25mg
    Price:
    $276
    Qty:
  10. Pack:
    10mg
    Price:
    $59
    Qty:
    Pack:
    50mg
    Price:
    $260
    Qty:
    Pack:
    20mM (add 1ml water)
    Price:
    $74
    Qty:
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