Group I (mGlu5, mGlu1)
Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
- Description:
Broad spectrum glutamate antagonist
Purity:>99%
Gatifloxacin (HB3263)
Description:Antibiotic; bacterial type II topoisomerase inhibitor. Activates ESC short term renewal.
Purity:>98%
GBR 12909 dihydrochloride (HB1812)
Description:Potent, competitive dopamine uptake inhibitor
Purity:>98%
Geldanamycin (HB3311)
Description:Selective Hsp90 inhibitor. Breast cancer stem cell inhibitor.
Purity:>98%
Genistein (HB2775)
Description:Protein tyrosine kinase inhibitor and PPARγ agonist. Phytoestrogen.
Purity:>98%