Cx43 hemichannel blocker. Shows no effect on gap junction coupling or at Panx-1 channels. Reduces mitochondrial potassium influx in cardiomyocytes and reduces infact size in a mouse ischemia model. Inhibits astroglial Cx43 hemichannels in a dose-dependent manner, without affecting gap junction channels.
Solubility & Handling
Solubility overview
Soluble in water (1 mg/ml)
Storage instructions
-20°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Understanding purity and quality - a guide for life scientists
