Group I (mGlu5, mGlu1)
Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
Bisindolylmaleimide IV (HB0137)
Description:Selective, non-competitive PKC / PKA inhibitor
Purity:>98%
- Description:
Selective, cell permeable PKC inhibitor
Purity:>98%
BIX 01294 (HB1413)
Description:Potent, selective GLP / G9a HMTase inhibitor. Potentiates iPSC induction.
Purity:>98%
BLZ-945 (HB4634)
Description:Potent, selective colony stimulating factor 1 receptor (CSF-1R) inhibitor
Purity:>95%
Borrelidin (HB3810)
Description:Antibiotic. Threonyl-tRNA synthetase (THrRS) inhibitor.
Purity:>98%