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Borrelidin

(HB3810)
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Product overview

Name Borrelidin
Purity >98%
Description Antibiotic. Threonyl-tRNA synthetase (THrRS) inhibitor.
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews
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Biological Data

Biological description Antibiotic. Threonyl-tRNA synthetase (THrRS) inhibitor. Cyclin-dependent kinase (CDK) inhibitor. Induces the collapse of formed capillary tubes in a dose-dependent fashion. In HUVECs, the capillary tube collapsing activity is mediated by the activation of caspases-3 and -8 and apoptosis induction. Shows anticancer, antiangiogenic and antiviral activity.

Solubility & Handling

Storage instructions +4°C
Solubility overview Soluble in DMSO
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name (1R,2R)-2-[(2S,4E,6Z,8R,9S,11R,13S,15S,16S)-7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]cyclopentanecarboxylic acid
Molecular Weight 489.6
Chemical structure Borrelidin [7184-60-3] Chemical Structure
Molecular Formula C28H43NO6
CAS Number 7184-60-3
PubChem identifier 6436801
SMILES O[C@@H](C1)[C@@H](C)C[C@@H](C)C[C@@H](C)C[C@H](C)[C@@H](O)\C(C#N)=C/C=C/C[C@]([C@]2([H])CCC[C@H]2C(O)=O)([H])OC1=O
Source Streptomyces sp.
InChi InChI=1S/C28H43NO6/c1-17-12-18(2)14-20(4)27(32)21(16-29)8-5-6-11-25(22-9-7-10-23(22)28(33)34)35-26(31)15-24(30)19(3)13-17/h5-6,8,17-20,22-25,27,30,32H,7,9-15H2,1-4H3,(H,33,34)/b6-5+,21-8-/t17-,18+,19-,20-,22+,23+,24-,25-,27+/m0/s1
InChiKey OJCKRNPLOZHAOU-TVHKGLGPSA-N
MDL number MFCD01740784
Appearance White to off-white powder
Grouped product items
Order: HB3810
Pack PriceQty
5mg
$386
Antibiotic. Threonyl-tRNA synthetase (THrRS) inhibitor.
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

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