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Borrelidin

(HB3810)
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Product overview

Name Borrelidin
Purity >98%
Description Antibiotic. Threonyl-tRNA synthetase (THrRS) inhibitor.
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews
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Biological Data

Biological description Antibiotic. Threonyl-tRNA synthetase (THrRS) inhibitor. Cyclin-dependent kinase (CDK) inhibitor. Induces the collapse of formed capillary tubes in a dose-dependent fashion. In HUVECs, the capillary tube collapsing activity is mediated by the activation of caspases-3 and -8 and apoptosis induction. Shows anticancer, antiangiogenic and antiviral activity.

Solubility & Handling

Solubility overview Soluble in DMSO
Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name (1R,2R)-2-[(2S,4E,6Z,8R,9S,11R,13S,15S,16S)-7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]cyclopentanecarboxylic acid
Molecular Weight 489.6
Chemical structure Borrelidin [7184-60-3] Chemical Structure
Molecular Formula C28H43NO6
CAS Number 7184-60-3
PubChem identifier 6436801
SMILES O[C@@H](C1)[C@@H](C)C[C@@H](C)C[C@@H](C)C[C@H](C)[C@@H](O)\C(C#N)=C/C=C/C[C@]([C@]2([H])CCC[C@H]2C(O)=O)([H])OC1=O
Source Streptomyces sp.
InChi InChI=1S/C28H43NO6/c1-17-12-18(2)14-20(4)27(32)21(16-29)8-5-6-11-25(22-9-7-10-23(22)28(33)34)35-26(31)15-24(30)19(3)13-17/h5-6,8,17-20,22-25,27,30,32H,7,9-15H2,1-4H3,(H,33,34)/b6-5+,21-8-/t17-,18+,19-,20-,22+,23+,24-,25-,27+/m0/s1
InChiKey OJCKRNPLOZHAOU-TVHKGLGPSA-N
MDL number MFCD01740784
Appearance White to off-white powder
Grouped product items
Order: HB3810
Pack PriceQty
5mg
$398
Antibiotic. Threonyl-tRNA synthetase (THrRS) inhibitor.
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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