Bisindolylmaleimide IX methansulfonate

(HB2958)
Technical documents: Datasheet

Product overview

Name Bisindolylmaleimide IX methansulfonate
Alternative names Bisindolylmaleimide IX
Purity >98%
Description Selective, cell permeable PKC inhibitor
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Biological Data

Biological description Selective and cell permeable protein kinase C (PKC) inhibitor. Inhibits the stimulation of insulin secretion by glucose. Inhibits T cell activation. Apoptosis inducer. Potent glycogen synthase kinase-3 (GSK-3) inhibitor. Transcription inhibitor. Induces TNF receptor family-mediated cell death. Pim-1 kinase inhibitor. Antitumor compound.

Solubility & Handling

Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Molecular Weight 553.7
Molecular Formula C25H23N5O2S.CH3SO3H
CAS Number 138489-18-6
PubChem identifier 11628205
SMILES CS(O)(=O)=O.CN1C=C(C2=CC=CC=C12)C1=C(C(=O)NC1=O)C1=CN(CCCSC(N)=N)C2=CC=CC=C12
InChiKey SAWVGDJBSPLRRB-UHFFFAOYSA-N
Appearance Red solid