Group I (mGlu5, mGlu1)
Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
Bicifadine hydrochloride (HB1787)
Description:Potent noradrenalin transporter antagonist. Also 5-HT and dopamine transporter antagonist.
Purity:>98%
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(+)-Bicuculline (HB0896)
Description:Prototypic, competitive GABAA receptor antagonist
Purity:>98%
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(-)-Bicuculline methiodide (HB0893)
Description:Prototypic, competitive GABAA receptor antagonist
Purity:>98%
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(-)-Bicuculline methobromide (HB0894)
Description:Prototypic, competitive GABAA receptor antagonist
Purity:>98%
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(-)-Bicuculline methochloride (HB0895)
Description:Prototypic, competitive GABAA receptor antagonist
Purity:>98%
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BIO (HB1259)
Description:Potent GSK-3α/β inhibitor. Maintains ESC self-renewal and pluripotency.
Purity:>98%
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