DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
-
-
Bisindolylmaleimide IV (HB0137)
Description:Selective, non-competitive PKC / PKA inhibitor
Purity:>98%
- Description:
Selective, cell permeable PKC inhibitor
Purity:>98%
-
-
-
BIX 01294 (HB1413)
Description:Potent, selective GLP / G9a HMTase inhibitor. Potentiates iPSC induction.
Purity:>98%
-
BLZ-945 (HB4634)
Description:Potent, selective colony stimulating factor 1 receptor (CSF-1R) inhibitor
Purity:>95%
-
Borrelidin (HB3810)
Description:Antibiotic. Threonyl-tRNA synthetase (THrRS) inhibitor.
Purity:>98%
