Selective protein kinase C (PKC) inhibitor. Competitive NQO2 inhibitor (Ki = 16.5 µM) and Ste20-related kinase (SLK) inhibitor (IC50 = 170 nM). Shows inhibitory action at PKCα, MSK1, MAPKAP-K1β, S6K1 and AMPK. Also CDK2 inhibitor (IC50 = 2 µM).
Solubility & Handling
Solubility overview
Soluble in methanol or DMSO
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.