DREADD

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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

Items 1-10 of 739

Set Descending Direction
  1. (D)-PPA 1 (HB7226)

    Description:

    PD-1/PD-L1 interaction inhibitor

    Pack:
    1mg
    Price:
    $200
    Qty:
  2. Description:

    Potent, highly selective iNOS inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $186
    Qty:
  3. 2-APB (HB1208)

    1  Review
    Top Reviews:
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    Description:

    IP3 receptor and store-operated channels (SOC) channel antagonist

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $58
    Qty:
    Pack:
    50mg
    Price:
    $191
    Qty:
  4. 7BIO (HB3732)

    Description:

    Aurora B and C kinase inhibitor

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $191
    Qty:
    Pack:
    50mg
    Price:
    $774
    Qty:
  5. Pack:
    25mg
    Price:
    $359
    Qty:
  6. Pack:
    50mg
    Price:
    $506
    Qty:
  7. A83-01 (HB3218)

    2  Reviews
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    Description:

    Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $88
    Qty:
    Pack:
    25mg
    Price:
    $297
    Qty:
  8. Pack:
    5mg
    Price:
    $90
    Qty:
    Pack:
    10mg
    Price:
    $135
    Qty:
    Pack:
    25mg
    Price:
    $303
    Qty:
    Pack:
    50mg
    Price:
    $538
    Qty:
  9. AACOCF3 (HB2354)

    Description:

    Selective cPLA2 inhibitor

    Pack:
    50mg
    Price:
    $604
    Qty:
  10. 17-AAG (HB3599)

    Description:

    Selective Hsp90 inhibitor. Also protects neuroprogenitor cells against apoptosis.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $133
    Qty:
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