DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
Amitriptyline hydrochloride (HB1794)
Description:Serotonin/norepinephrine reuptake inhibitor (SNRI)
Purity:>98%
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Anisomycin (HB2239)
Description:Protein synthesis inhibitor. Potent JNK / p38 MAPK activator.
Purity:>98%
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DL-AP4 Sodium salt (HB0250)
Description:Water soluble form of DL-AP4, non-selective glutamate antagonist
Purity:>99%
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D-AP5 (HB0225)
Description:Selective, competitive NMDA receptor antagonist. Inhibits NMDAR-synaptic plasticity.
Purity:>99%
