DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
ZM 447439 (HB1444)
Description:Potent, selective, ATP-competitive Aurora kinase B inhibitor
Purity:>99%
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Zoniporide dihydrochloride (HB1137)
Description:Potent, selective Na+ / H+ exchanger-1 inhibitor
Purity:>99%
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Zotepine (HB1778)
Description:5-HT2A and dopamine D2 receptor antagonist. Atypical antipsychotic.
Purity:>99%
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Z-VAD-(OMe)-FMK (HB1319)
Description:Irreversible, cell permeable, broad spectrum caspase inhibitor.
Purity:>95%
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Z-VRPR-FMK (HB4138)
Description:Selective, cell permeable and irreversible MALT1 inhibitor
Purity:>90%
