Product overview

Name Z-VRPR-FMK
Purity >90%
Description Selective, cell permeable and irreversible MALT1 inhibitor
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Biological Data

Biological description Selective cell permeable and irreversible MALT1 inhibitor. Inhibits NF-kappaB-dependent gene expression and affects the growth, proliferation and survival of activated B cell-like diffuse large B cell lymphomas (ABC-DLBCL) and germinal center B cell like diffuse large B cell lymphoma (GCB-DLBCL) cell lines. Shown to inhibit the autoprocessing activity of MCA2ac (calcium dependent) in Trypanosoma brucei.

Solubility & Handling

Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Purity >90%
Molecular Weight 790.8
Chemical structure Z-VRPR-FMK [1381885-28-4 (free base)] Chemical Structure
Molecular Formula C31H49FN10O6.CF3CO2H
CAS Number 1381885-28-4 (free base)
PubChem identifier 121513848
SMILES OC(=O)C(F)(F)F.CC(C)[C@H](NC(=O)OCC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)NC(CCCNC(N)=N)C(=O)CF
InChiKey WIPHXOQUHDJLCU-WTJMUODPSA-N
Appearance White to slightly yellow solid