Product overview

Name Z-VRPR-FMK
Purity >90%
Description Selective, cell permeable and irreversible MALT1 inhibitor
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Biological Data

Biological description Selective cell permeable and irreversible MALT1 inhibitor. Inhibits NF-kappaB-dependent gene expression and affects the growth, proliferation and survival of activated B cell-like diffuse large B cell lymphomas (ABC-DLBCL) and germinal center B cell like diffuse large B cell lymphoma (GCB-DLBCL) cell lines. Shown to inhibit the autoprocessing activity of MCA2ac (calcium dependent) in Trypanosoma brucei.

Solubility & Handling

Storage instructions +4°C
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >90%
Molecular Weight 790.8
Chemical structure Z-VRPR-FMK [1381885-28-4 (free base)] Chemical Structure
Molecular Formula C31H49FN10O6.CF3CO2H
CAS Number 1381885-28-4 (free base)
PubChem identifier 121513848
SMILES OC(=O)C(F)(F)F.CC(C)[C@H](NC(=O)OCC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)NC(CCCNC(N)=N)C(=O)CF
InChiKey WIPHXOQUHDJLCU-WTJMUODPSA-N
Appearance White to slightly yellow solid