Zotepine

(HB1778)

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Product overview

Name Zotepine
Purity >99%
Description 5-HT2A and dopamine D2 receptor antagonist. Atypical antipsychotic.
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Biological Data

Biological description 5-HT2A and D2 receptor antagonist (Ki values are 0.69 and 2.3 nM respectively). Also a potent histamine H1 receptor antagonist (IC50 = 8.0 nM). Atypical antipsychotic. Shows antidepressive and anxiolytic effects. Active in vivo.

Solubility & Handling

Solubility overview Soluble in DMSO (50mM)
Storage instructions Room temperature
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >99%
Chemical name 2-[(8-Chlorodibenzo(Z)[b,f]thiepin- 10-yl)oxy]-N,N-dimethylethanamine
Molecular Weight 331.86
Molecular Formula C18H18ClNOS
CAS Number 26615-21-4
PubChem identifier 5736
SMILES ClC3=CC=C2SC1=CC=CC=C1C=C(OCCN(C)C)C2=C3
InChiKey HDOZVRUNCMBHFH-UHFFFAOYSA-N