DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
Anti-GST tag antibody ValidAbTM (HB9897)
Description:Antibody to the GST tag - widely used as a protein tag in molecular biology. Part of the ValidAbâ„¢ range of highly validated, data-rich antibodies.Â
Host: MouseClonality: MonoclonalReactivity Tested: Species IndependentGYKI 52466 hydrochloride (HB0311)
Description:Selective, non-competitive AMPA receptor antagonist
Purity:>98%
GYKI 53655 hydrochloride (HB0312)
Description:Non-competitive AMPA receptor antagonist. Also blocks kainate GluK3 homomeric receptors.
Purity:>98%
Anti-Histone H3 antibody ValidAbâ„¢ (HB6980)
Description:Antibody to Histone H3 - Histone protein used as a loading control for western blotting. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: RabbitClonality: PolyclonalReactivity Tested: Mouse, Rat