G protein coupled receptors
G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
View products: ACh Muscarinic | Adrenoceptors | Adenosine | Cannabinoid | Dopamine | GABAB | Histamine | Metabotropic Glutamate Receptors | Opioid | Peptide Receptors | Purinergic P2Y | Serotonin (5HT) | Neuroscience Research Tools
Cycloheximide (HB2904)
Description:Eukaryotic protein synthesis inhibitor. Apoptosis inducer.
Purity:>95%
Cyclosporin A (HB0220)
Description:Potent calcineurin inhibitor. Inhibits MPTP opening.
Purity:>99%
DAPI Staining Solution (1mg/mL) (HB8199)
Description:Blue fluorescent DNA stain. Nuclear counterstain. 1mg/mL staining solution in water. Solid also available in 10mg and 50mg packs.
DAPT (HB3345)
Description:γ-secretase inhibitor and classical notch inhibitor. Induces neuronal differentiation. 3D Growth matrix component and used in cerebral organoid differentiation media.
Purity:>98%
Daunorubicin hydrochloride (HB4376)
Description:RNA and DNA synthesis inhibitor. Antibiotic.
Purity:>98%
Dexamethasone (HB2521)
Description:Anti-inflammatory synthetic glucocorticoid. Induces hMSC differentiation. Apoptosis inducer.
Purity:>98%
Dexamethasone (water-soluble) (HB6020)
Description:Synthetic glucocorticoid with potent anti-inflammatory actions. Induces hMSC differentiation. Apoptosis inducer. Water soluble and suitable for cell culture.Â
Purity:>98%