G protein coupled receptors
G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
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Naspm trihydrochloride (HB0441)
Description:Selective GluA2- lacking, Ca2+ permeable AMPA / kainate receptor antagonist
Purity:>95%
NBQX disodium salt (HB0443)
Description:Potent, selective, competitive AMPA receptor antagonist. Disodium salt.
Purity:>99%
Necrostatin-5 (HB3994)
Description:Necroptosis inhibitor. Indirect RIP1 kinase inhibitor.
Purity:>98%
Necrostatin-7 (HB3995)
Description:Necroptosis inhibitor. Shows no action at RIP1 kinase.
Purity:>98%
Anti-NeuN antibody ValidAbâ„¢ (HB6498)
Description:Antibody to NeuN - marker for mature neurones expressed in the nucleus. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: RabbitClonality: PolyclonalReactivity Tested: Mouse, RatAnti-NeuN antibody ValidAbâ„¢ (HB9493)
Description:Antibody to NeuN - marker for mature neurones expressed in the nucleus. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: GoatClonality: PolyclonalReactivity Tested: Mouse, RatAnti-NeuN antibody ValidAbâ„¢ (HB6429)
Description:Antibody to NeuN - marker for mature neurones expressed in the nucleus. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: Mouse, Rat- Description:
Antibody to Neurofilament L - neurofilament component expressed in neurones. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: Mouse, Rat