Ionotropic glutamate receptors
Ionotropic glutamate receptors (NMDA, AMPA and Kainate receptors) are cation-selective tetramers formed by multimeric assemblies of subunits. AMPA receptors comprise of homomers or heteromers of GluA1, GluA2, GluA3 and GluA4 subunits. NMDA receptors are heteromic assemblies of GluN1, GluN2A, GluN2B, GluN2C, GluN2D, GluN3A and GluN3B. Kainate receptors can be expressed as homomers of GluK1, GluK2 or GluK3. Researchers can save up to 50% on potent & selective NMDA, AMPA and Kainate receptor antagonists, agonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
View resources: Ionotropic Receptor Nomenclature Guide | NMDA Receptor Mini-Review | NMDAR Associated Proteins
View products:Â AMPA | Kainate | NMDA
CAT335 (HB8146)
Description:K2P2.1 (TREK-1) modulator. Used with ML336 as part of the CATKLAMP chemogenetic strategy. Selectively and irreversibly activates TREK-1CG* but not wild-type K2P2.1 (TREK-1)
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Purity:>98%
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ML 336 (K2P2.1/ TREK-1 modulator) (HB7386)
Description:Covalent K2P2.1 (TREK-1) modulator. Used with CAT335 as part of the CATKLAMP chemogenetic strategy.
Purity:>99%
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Riluzole (HB6093)
Description:Na+ channel blocker / glutamate inhibitor. TREK-1 K2P channel activator.
Purity:>98%
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Riluzole hydrochloride (HB0548)
Description:Na+ channel blocker / glutamate inhibitor. TREK-1 K2P channel activator. Water soluble.
Purity:>98%
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Spadin (HB5438)
Description:Potent TREK-1/ K2P2.1 channel blocker. Shows fast-acting antidepressant effects.
