Ion channels
Ion channels are specialised pore-forming membrane proteins that allow ions to pass through the channel pore. They are classifed by their gating mechanism (eg. voltage-gated, ligand-gated, cyclic-nucleotide-gated & mechanosensitive) or ion selectivity (eg. calcium, potassium, sodium, chloride, proton). Researchers can save up to 50% on selective ion channel activators and blockers from Hello Bio - they are up to half the price of other suppliers.
View products: Voltage-Gated Ion Channels | Ligand-Gated Ion Channels (Ionotropic Receptors) | Ionophores | PiezoView Resources: Ion Channel Modulators
- Description:
Water soluble Toll-like receptor 7 (TLR7) agonist. Stimulates cytokine production.
Purity:>98%
Ionomycin calcium salt (HB1001)
Description:Calcium ionophore. Stimulates cytokine production.
Purity:>98%
Ionomycin free acid (HB1002)
Description:Calcium ionophore. Stimulates cytokine production.
Purity:>98%
LIH383 (HB9242)
Description:Potent and selective ACKR3 (CXCR7) agonist. Potentiates opioid peptide activity.
- Description:
Novel, intracellular covalent chemokine CCR2 negative allosteric modulator (NAM). Binds irreversibly.
Monensin sodium salt (HB4882)
Description:Protein transport inhibitor. Commonly used in cytokine staining.
Purity:>98%
- Description:
PKC activator. Widely used for THP-1 cell differentiation and with ionomycin for stimulating cytokine production
Purity:>99%
SP600125 (HB2234)
Description:Selective, ATP-competitive JNK inhibitor. Prevents BMP9-induced osteogenic MSC differentiation. Maintains stem cells in naive pluripotent state.
Purity:>98%