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Imiquimod hydrochloride (water soluble)

(HB8528)
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Product overview

Name Imiquimod hydrochloride (water soluble)
Alternative names R 837, R-837, R837
Purity >98%
Description

Water soluble Toll-like receptor 7 (TLR7) agonist. Stimulates cytokine production.

Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (2)
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Biological Data

Biological description Water soluble TLR7 agonist and Caspase-3 activator. Immune response modulator. Stimulates proinflammatory cytokine production and activates NF-κB. Shows antiproliferative, antiviral, anti-inflammatory and anti-cancer actions. Also induces apoptosis.

Solubility & Handling

Solubility overview Soluble in water (5 mg/ml with warming), in ethanol (5 mg/ml with warming), and in DMSO (2 mg/ml)
Storage instructions Room temperature
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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More Info

Dilution

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Chemical Data

Purity >98%
Chemical name 4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline hydrochloride
Molecular Weight 276.11
Chemical structure Imiquimod hydrochloride [99011-78-6] Chemical Structure
Molecular Formula C14H16N4.HCl
CAS Number 99011-78-6
PubChem identifier 13982876
SMILES CC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N.Cl
Source Synthetic
InChi InChI=1S/C14H16N4.ClH/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12)15;/h3-6,8-9H,7H2,1-2H3,(H2,15,17);1H
InChiKey RGKLRAHQVIHCCH-UHFFFAOYSA-N
Appearance White solid

References for Imiquimod hydrochloride (water soluble)

References are publications that support the biological activity of the product

  • The antitumoral mode of action of imiquimod and other imidazoquinolines.

    Schön M et al (2007) Current medicinal chemistry 14 : 681-7
    Read more (PubMedID: 17346155)

  • The pharmacology of endosomal TLR agonists in viral disease.

    Averett DR et al (2007) Biochemical Society transactions 35 : 1468-72
    Read more (PubMedID: 18031247)

2 Item(s)

Related Products
Grouped product items
Order: HB8528
Pack PriceQty
5mg
$29
50mg
$52
100mg
$77
250mg
$147

Water soluble Toll-like receptor 7 (TLR7) agonist. Stimulates cytokine production.

Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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