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Imiquimod hydrochloride (water soluble)

(HB8528)
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Technical documents: CoA Datasheet

Product overview

Name Imiquimod hydrochloride (water soluble)
Alternative names R 837, R-837, R837
Purity >98%
Description

Water soluble Toll-like receptor 7 (TLR7) agonist. Stimulates cytokine production.

Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (2)
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Biological Data

Biological description Water soluble TLR7 agonist and Caspase-3 activator. Immune response modulator. Stimulates proinflammatory cytokine production and activates NF-κB. Shows antiproliferative, antiviral, anti-inflammatory and anti-cancer actions. Also induces apoptosis.

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in water (5 mg/ml with warming), in ethanol (5 mg/ml with warming), and in DMSO (2 mg/ml)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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More Info

Dilution

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Chemical Data

Purity >98%
Chemical name 4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline hydrochloride
Molecular Weight 276.11
Chemical structure Imiquimod hydrochloride [99011-78-6] Chemical Structure
Molecular Formula C14H16N4.HCl
CAS Number 99011-78-6
PubChem identifier 13982876
SMILES CC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N.Cl
Source Synthetic
InChi InChI=1S/C14H16N4.ClH/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12)15;/h3-6,8-9H,7H2,1-2H3,(H2,15,17);1H
InChiKey RGKLRAHQVIHCCH-UHFFFAOYSA-N
Appearance White solid

References for Imiquimod hydrochloride (water soluble)

References are publications that support the biological activity of the product

  • The antitumoral mode of action of imiquimod and other imidazoquinolines.

    Schön M et al (2007) Current medicinal chemistry 14 : 681-7
    Read more (PubMedID: 17346155)

  • The pharmacology of endosomal TLR agonists in viral disease.

    Averett DR et al (2007) Biochemical Society transactions 35 : 1468-72
    Read more (PubMedID: 18031247)

2 Item(s)

Related Products
Grouped product items
Order: HB8528
Pack PriceQty
5mg
$28
50mg
$50
100mg
$75
250mg
$143

Water soluble Toll-like receptor 7 (TLR7) agonist. Stimulates cytokine production.

Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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