DNA methyltransferase (DNMT)

Acyl-CoA cholesterol acyltransferase 1 and 2 inhibitor

Rock inhibitor. Improves hESCs survival and fibroblast reprogramming efficiency and iPSCs induction.

Competitive hypoxanthine-guanine phosphoribosyltransferase substrate

LSD1 / MAO inhibitor. Enables reprogramming of mouse embryonic fibroblasts into iPS cells.

Potent HDAC inhibitor. Induces hiPSCs differentiation to cardiogenic cells and induces accelerated dedifferentiation of primordial germ cells.

ER Stress inducer which induces cell death

Potent, selective G9a HMTase inhibitor

Potent, selective G9a / GLP HMTase inhibitor

Histone deacetylase inhibitor. Shows multitude of biological actions. Enables pluripotent stem cell induction from somatic cells.

Potent tankyrase inhibitor. Wnt signaling inhibitor.