DNA methyltransferase (DNMT)

Manumycin A derivative

Potent PORCN inhibitor

Potent Wnt pathway inhibitor and PORCN inhibitor. Suppresses R1 ESC self-renewal. Used in the production of cardiac organoids.

Potent PORCN inhibitor. Supresses R1 ESCs self renewal.

Potent CDK inhibitor. Also GSK-3 inhibitor. Generates iPSCs.

Acyl-CoA cholesterol acyltransferase (ACAT) inhibitor

Potent MGMT inhibitor

Rasfarnesyltransferase inhibitor

Broad spectrum antibiotic. Potent microglial activation inhibitor. Allows formation of EPSs.

Oct4 activator. Enhances iPSC reprogramming efficiency.