Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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    $94
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    $842
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  3. Wnt-C59 (HB3155)

    Description:

    Highly potent PORCN inhibitor. Induces iPSC cardiomyocytes differentiation.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $271
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    50mg
    Price:
    $1,056
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  4. Wogonin (HB4126)

    Description:

    Cell permeable COX-2 inhibitor. Increase NO production.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $101
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    25mg
    Price:
    $397
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  5. Wortmannin (HB2778)

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    Description:

    Potent, selective, irreversible PI3-K inhibitor

    Purity:

    >99%

    Pack:
    1mg
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    Pack:
    5mg
    Price:
    $257
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    Pack:
    10mg
    Price:
    $475
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  6. Description:

    Serotonin/norepinephrine reuptake inhibitor (SNRI)

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $517
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  7. Xanthorrhizol (HB4127)

    Description:

    Potent COX-2 and iNOS inhibitor

    Purity:

    >97%

    Pack:
    1mg
    Price:
    $179
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  8. Pack:
    10mg
    Price:
    $189
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    Pack:
    50mg
    Price:
    $734
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  9. XAV 939 (HB0660)

    Description:

    Potent tankyrase inhibitor. Wnt/β-catenin signaling inhibitor.

    Purity:

    >98%

    Pack:
    5mg
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    Qty:
    Pack:
    10mg
    Price:
    $115
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    Pack:
    25mg
    Price:
    $257
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    Pack:
    50mg
    Price:
    $465
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