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PTP Inhibitor IV

(HB0539)
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Product overview

Name PTP Inhibitor IV
Purity >95%
Description PTP inhibitor
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3)
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Biological Data

Biological description Protein tyrosine phosphatase (PTP) inhibitor. Attenuates oligodendrocyte maturation. Impairs the differentiation of endothelial cells. Shows anti-angiogenic actions.

Solubility & Handling

Solubility overview Soluble in DMSO (10mg/ml) or ACN.
Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >95%
Chemical name N,N'-[1,4-phenylenebis[(1-methylethylidene)-4,1-phenylene]]bis[1,1,1-trifluoro-methanesulfonamide
Molecular Weight 608.6
Molecular Formula C26H26F6N2O4S2
CAS Number 329317-98-8
PubChem identifier 6420094
SMILES CC(C)(C1=CC=C(C=C1)C(C)(C)C2=CC=C(C=C2)NS(=O)(=O)C(F)(F)F)C3=CC=C(C=C3)NS(=O)(=O)C(F)(F)F
InChi InChI=1S/C26H26F6N2O4S2/c1-23(2,19-9-13-21(14-10-19)33-39(35,36)25(27,28)29)17-5-7-18(8-6-17)24(3,4)20-11-15-22(16-12-20)34-40(37,38)26(30,31)32/h5-16,33-34H,1-4H3
InChiKey JWNAVYMNAQDLHX-UHFFFAOYSA-N

References for PTP Inhibitor IV

References are publications that support the biological activity of the product

  • SHP-2 promotes the maturation of oligodendrocyte precursor cells through Akt and ERK1/2 signaling in vitro.

    Liu X et al (2011) PLoS One 6(6) : e21058.
    Read more (PubMedID: 21701583)

  • Phosphatase inhibitors with anti-angiogenic effect in vitro.

    Sylvest L et al (2010) APMIS 118(1) : 49-59.
    Read more (PubMedID: 20041871)

  • PTP inhibitor IV protects JNK kinase activity by inhibiting dual-specificity phosphatase 14 (DUSP14).

    Park JE et al (2009) Biochem Biophys Res Commun 387(4) : 795-9.
    Read more (PubMedID: 19646420)

3 Item(s)

Grouped product items
Order: HB0539
Pack PriceQty
10mg
$203
PTP inhibitor
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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