Product overview

Name PTP1B Inhibitor
Purity >95%
Description PTP1B inhibitor
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Biological Data

Biological description Protein tyrosine phosphatase 1B (PTP1B) inhibitor. Enhances insulin action.

Solubility & Handling

Solubility overview Soluble in DMSO or ethanol
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >95%
Molecular Weight 741.5
Chemical structure PTP1B Inhibitor  [765317-72-4] Chemical Structure
Molecular Formula C26H19Br2N3O7S3
CAS Number 765317-72-4

References for PTP1B Inhibitor

References are publications that support the biological activity of the product
  • Protein tyrosine phosphatase 1B regulates TGF beta 1-induced Smad2 activation through PI3 kinase-dependent pathway.

    Sun T et al (2006) Cytokine 35(1-2) : 88-94.
  • Allosteric inhibition of protein tyrosine phosphatase 1B.

    Wiesmann C et al (2004) Nat Struct Mol Biol 11(8) : 730-7.

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