Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 471-480 of 718

Set Descending Direction
  1. PD 0325901 (HB2240)

    Description:

    Potent MEK1 and MEK2 inhibitor. Enhances iPSCs generation. Used in organoid production.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    Qty:
    Pack:
    2mg
    Price:
    $28
    Qty:
    Pack:
    5×2mg
    Price:
    $115
    Qty:
    Pack:
    10mg
    Price:
    $109
    Qty:
    Pack:
    50mg
    Price:
    $308
    Qty:
  2. PD 102807 (HB1509)

    Description:

    Potent, selective M4 receptor antagonist. Promotes erythroid progenitors expansion.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $287
    Qty:
  3. PD 150,606 (HB4018)

    Description:

    Selective, cell permeable calpain inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $411
    Qty:
  4. PD 173074 (HB3584)

    Description:

    FGFR1/ FGFR3 inhibitor. Inhibits oligodendrocyte progenitor proliferation and differentiation.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $215
    Qty:
    Pack:
    50mg
    Price:
    $835
    Qty:
  5. Pack:
    1mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $100
    Qty:
    Pack:
    50mg
    Price:
    $448
    Qty:
  6. Pack:
    5mg
    Price:
    $91
    Qty:
    Pack:
    25mg
    Price:
    $367
    Qty:
  7. Pellitorine (HB4019)

    Description:

    ACAT (Acyl-CoA cholesteryl acyl transferase) inhibitor. Tingling-inducing agent.

    Purity:

    >97%

    Pack:
    5mg
    Price:
    $493
    Qty:
  8. Penicillide (HB4020)

    Description:

    Acyl-CoA-cholesterol acyltransferase (ACAT) inhibitor

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $183
    Qty:
  9. Pack:
    1mg
    Price:
    $116
    Qty:
    Pack:
    5mg
    Price:
    $475
    Qty:
  10. Pack:
    500μg
    Price:
    $163
    Qty:
    Pack:
    1mg
    Price:
    $261
    Qty:
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