Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Pack:
    10mg
    Price:
    $105
    Qty:
    Pack:
    50mg
    Price:
    $418
    Qty:
  2. Paxilline (HB1056)

    Description:

    Potent, reversible, selective KCa channel inhibitor. Also SERCA inhibitor.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $153
    Qty:
  3. Pack:
    50mg
    Price:
    $534
    Qty:
  4. PD 0325901 (HB2240)

    Description:

    Potent MEK1 and MEK2 inhibitor. Enhances iPSCs generation. Used in organoid production.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    Qty:
    Pack:
    2mg
    Price:
    $29
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    Pack:
    5×2mg
    Price:
    $120
    Qty:
    Pack:
    10mg
    Price:
    $114
    Qty:
    Pack:
    50mg
    Price:
    $321
    Qty:
  5. PD 102807 (HB1509)

    Description:

    Potent, selective M4 receptor antagonist. Promotes erythroid progenitors expansion.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $300
    Qty:
  6. PD 150,606 (HB4018)

    Description:

    Selective, cell permeable calpain inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $423
    Qty:
  7. PD 173074 (HB3584)

    Description:

    FGFR1/ FGFR3 inhibitor. Inhibits oligodendrocyte progenitor proliferation and differentiation.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $225
    Qty:
    Pack:
    50mg
    Price:
    $870
    Qty:
  8. Pack:
    1mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $103
    Qty:
    Pack:
    50mg
    Price:
    $462
    Qty:
  9. Pack:
    5mg
    Price:
    $94
    Qty:
    Pack:
    25mg
    Price:
    $378
    Qty:
  10. Pellitorine (HB4019)

    Description:

    ACAT (Acyl-CoA cholesteryl acyl transferase) inhibitor. Tingling-inducing agent.

    Purity:

    >97%

    Pack:
    5mg
    Price:
    $508
    Qty:
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