Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 401-410 of 718

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  2. Description:

    Highly selective, pan-Akt inhibitor. Autophagy and apoptosis inducer. Orally bioavailable.

    Purity:

    >98%

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    5mg
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    10mg
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    $77
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    $325
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    10mM solution (in 1mL DMSO)
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    $125
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  3. Description:

    Selective leukotriene LTD4 receptor antagonist. Potent MRP1 inhibitor.

    Purity:

    >97%

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    25mg
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    $276
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    10mg
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    $59
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    50mg
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    $260
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    20mM (add 1ml water)
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    $74
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    10mg
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    $66
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    50mg
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    $248
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    10mM (add 1ml water)
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    $50
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    10mg
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    $123
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    50mg
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    $488
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  7. 8  Reviews
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    Description:

    Caged glutamate that rapidly and efficiently releases glutamate when photolysed

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $165
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    Pack:
    50mg
    Price:
    $681
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  8. Moclobemide (HB1791)

    Description:

    Reversible MAO-A inhibitor

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $109
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    Pack:
    50mg
    Price:
    $436
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  9. MOG (35-55) (HB5273)

    Description:

    Myelin oligodendrocyte glycoprotein fragment. Induces experimental multiple sclerosis-like disease.

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $176
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