Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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    5mg
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    $118
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    10mg
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    $209
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    25mg
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    $495
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  2. Mifepristone (HB2783)

    Description:

    Potent glucocorticoid and progesterone receptor antagonist. Also used for gene editing as a mifepristone inducible Cas9 and Cpf1 CRISPR effector.

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $86
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  3. Description:

    5-HT and norepinephrine re-uptake inhibitor (SNRI)

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $126
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    50mg
    Price:
    $445
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    25mg
    Price:
    $90
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    50mg
    Price:
    $136
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    100mg
    Price:
    $203
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    500mg
    Price:
    $806
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  5. Description:

    Highly selective, pan-Akt inhibitor. Autophagy and apoptosis inducer. Orally bioavailable.

    Purity:

    >98%

    Pack:
    5mg
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    10mg
    Price:
    $78
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    50mg
    Price:
    $329
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    Pack:
    10mM solution (in 1mL DMSO)
    Price:
    $127
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  6. Description:

    Selective leukotriene LTD4 receptor antagonist. Potent MRP1 inhibitor.

    Purity:

    >97%

    Pack:
    25mg
    Price:
    $284
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  7. Pack:
    10mg
    Price:
    $69
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    50mg
    Price:
    $259
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    Pack:
    10mM (add 1ml water)
    Price:
    $52
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  8. Pack:
    10mg
    Price:
    $60
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    Pack:
    50mg
    Price:
    $263
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    Pack:
    20mM (add 1ml water)
    Price:
    $75
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  9. Pack:
    10mg
    Price:
    $127
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    Pack:
    50mg
    Price:
    $503
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