Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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    10mg
    Price:
    $271
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    Price:
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    Description:

    Potent and selective 5-HT2A receptor antagonist. Water soluble.

    Pack:
    10mg
    Price:
    $296
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    Pack:
    50mg
    Price:
    $1,126
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  4. Description:

    Inhibits α-MSH release inhibitors. Also increase dopamine levels.

    Pack:
    10mg
    Price:
    $77
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  5. Pack:
    100mg
    Price:
    $188
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  6. Metergoline (HB1623)

    Description:

    5-HT1/5-HT2 antagonist. Shows affinity for 5-HT6 and 5-HT7.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $90
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    Pack:
    50mg
    Price:
    $265
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  7. Description:

    L-aromatic amino acid decarboxylase inhibitor

    Pack:
    1g
    Price:
    $111
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  8. Description:

    Potent, selective α7 nicotinic receptor antagonist

    Purity:

    >95%

    Pack:
    5mg
    Price:
    $73
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    Pack:
    25mg
    Price:
    $270
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  9. MG132 (HB4135)

    Description:

    Potent, cell-permeable proteasome inhibitor. Calpain inhibitor. Apoptosis inducer.

    Purity:

    >95%

    Pack:
    5mg
    Price:
    $107
    Free trial
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    Pack:
    25mg
    Price:
    $313
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  10. MHY 1485 (HB7154)

    Description:

    mTOR activator and autophagy inhibitor. Cell-permeable.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $58
    Qty:
    Pack:
    50mg
    Price:
    $182
    Qty:
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