Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 391-400 of 718

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  1. Pack:
    10mg
    Price:
    $263
    Qty:
    Pack:
    50mg
    Price:
    $1,003
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  2. Description:

    Inhibits α-MSH release inhibitors. Also increase dopamine levels.

    Pack:
    10mg
    Price:
    $75
    Qty:
  3. Pack:
    100mg
    Price:
    $183
    Qty:
  4. Metergoline (HB1623)

    Description:

    5-HT1/5-HT2 antagonist. Shows affinity for 5-HT6 and 5-HT7.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $87
    Qty:
    Pack:
    50mg
    Price:
    $257
    Qty:
  5. Description:

    L-aromatic amino acid decarboxylase inhibitor

    Pack:
    1g
    Price:
    $108
    Qty:
  6. MG132 (HB4135)

    Description:

    Potent, cell-permeable proteasome inhibitor. Calpain inhibitor. Apoptosis inducer.

    Purity:

    >95%

    Pack:
    5mg
    Price:
    $103
    Free trial
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    Pack:
    25mg
    Price:
    $300
    Qty:
  7. MHY 1485 (HB7154)

    Description:

    mTOR activator and autophagy inhibitor. Cell-permeable.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $58
    Qty:
    Pack:
    50mg
    Price:
    $182
    Qty:
  8. Pack:
    5mg
    Price:
    $113
    Qty:
    Pack:
    10mg
    Price:
    $201
    Qty:
    Pack:
    25mg
    Price:
    $474
    Qty:
  9. Mifepristone (HB2783)

    Description:

    Potent glucocorticoid and progesterone receptor antagonist. Also used for gene editing as a mifepristone inducible Cas9 and Cpf1 CRISPR effector.

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $85
    Qty:
  10. Description:

    5-HT and norepinephrine re-uptake inhibitor (SNRI)

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $122
    Qty:
    Pack:
    50mg
    Price:
    $432
    Qty:
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