Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 21-30 of 39

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    10mg
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    $151
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    25mg
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    $312
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    50mg
    Price:
    $529
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  3. PD 0325901 (HB2240)

    Description:

    Potent MEK1 and MEK2 inhibitor. Enhances iPSCs generation. Used in organoid production.

    Purity:

    >98%

    Pack:
    1mg
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    2mg
    Price:
    $28
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    Pack:
    5×2mg
    Price:
    $115
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    Pack:
    10mg
    Price:
    $109
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    50mg
    Price:
    $308
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  4. Pifithrin-μ (HB3025)

    Description:

    p53 inhibitor. Supresses eSC self renewal and may increase stem cell reprogramming efficiency.

    Purity:

    >99%

    Pack:
    5mg
    Price:
    $95
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    Pack:
    25mg
    Price:
    $382
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  5. RepSox (HB3301)

    Description:

    Potent, selective TGF-βRI inhibitor. Enhances cellular reprogramming efficiency.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $134
    Qty:
    Pack:
    25mg
    Price:
    $279
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  6. RG 108 (HB1377)

    Description:

    Non-nucleoside DNA methyltransferase inhibitor. Enhances iPSC generation efficiency.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $97
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    Pack:
    50mg
    Price:
    $382
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  7. Pack:
    10mg
    Price:
    $116
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    Pack:
    50mg
    Price:
    $327
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  8. SB 431542 (HB3555)

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    Description:

    Potent, selective TGF-βRI ALK5, ALK4, ALK7 inhibitor. Induces sheet formation, proliferation, differentiation of ESC-derived endothelial cells and replaces SOX2 in reprogramming protocols.3D growth matrix component and can be used in production of organoids.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $109
    Qty:
    Pack:
    5mg
    Price:
    $153
    Free trial
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    Pack:
    2x5mg
    Price:
    $240
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    Pack:
    10mg
    Price:
    $233
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    Pack:
    25mg
    Price:
    $508
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    Pack:
    50mg
    Price:
    $959
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    Pack:
    10mM (1mL in DMSO)
    Price:
    $154
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