Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 1-10 of 39

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  1. AK-7 (HB3747)

    Description:

    Brain-permeable SIRT2 (sirtuin 2) inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $494
    Qty:
  2. Pack:
    10mg
    Price:
    $743
    Qty:
    Pack:
    5mg
    Price:
    $499
    Qty:
  3. L-Ascorbic acid (HB1238)

    Description:

    Antioxidant. Enhances iPSC generation and increases reprogramming efficiency. Supports mesenchymal stem cell proliferation.

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $86
    Qty:
    Pack:
    1g
    Price:
    $28
    Qty:
    Pack:
    25g
    Price:
    $42
    Qty:
    Pack:
    100g
    Price:
    $100
    Qty:
  4. 5-Azacytidine (HB1374)

    Description:

    DNA methyltransferase inhibitor. Improves stem cell reprogramming efficiency and induces differentiation of MSCs into cardiomyocytes.

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $69
    Qty:
    Pack:
    250mg
    Price:
    $95
    Qty:
  5. Description:

    L-type Ca2+ channel agonist. Aids iPSCs generation from Mouse embryonic fibroblasts.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $124
    Qty:
    Pack:
    50mg
    Price:
    $517
    Qty:
  6. BIX 01294 (HB1413)

    Description:

    Potent, selective GLP / G9a HMTase inhibitor. Potentiates iPSC induction.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $213
    Qty:
    Pack:
    50mg
    Price:
    $743
    Qty:
  7. 4  Reviews
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    Description:

    Thymidine analog. Widely used to identify proliferating cells, enhances Yamanaka factor reprogramming

    Purity:

    >98%

    Pack:
    250mg
    Price:
    $54
    Qty:
    Pack:
    500mg
    Price:
    $78
    Qty:
    Pack:
    1g
    Price:
    $133
    Qty:
    Pack:
    5g
    Price:
    $409
    Qty:
  8. CHIR 99021 (HB1261)

    Description:

    Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $48
    Qty:
    Pack:
    2mg
    Price:
    Qty:
    Pack:
    5×2mg
    Price:
    $180
    Qty:
    Pack:
    10mg
    Price:
    $175
    Qty:
    Pack:
    5mg
    Price:
    $112
    Qty:
    Pack:
    25mg
    Price:
    $427
    Qty:
    Pack:
    50mg
    Price:
    $727
    Qty:
    Pack:
    10mM (1mL in DMSO)
    Price:
    $121
    Qty:
  9. Description:

    Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons. Water soluble.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $220
    Qty:
    Pack:
    50mg
    Price:
    $879
    Qty:
  10. Pack:
    10mg
    Price:
    $152
    Qty:
    Pack:
    50mg
    Price:
    $579
    Qty:
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