Histone deacetylase (HDAC)
Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.
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PKC activator. Widely used for THP-1 cell differentiation and with ionomycin for stimulating cytokine production
Purity:>99%
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Phosphatase Inhibitor Cocktail powder for use in cell lysates and tissue extracts including samples containing detergents.
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Phosphatase Inhibitor Cocktail solution for use in cell lysates and tissue extracts including samples containing detergents.
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Phosphatase Inhibitor Cocktail solution (with Calyculin A) for the inhibition of serine/threonine and alkaline phosphatases.
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