Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Pack:
    50mg
    Price:
    $645
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  2. SNX 482 (HB1235)

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    Description:

    Reported to be a potent, selective Cav2.3 (R-type) channel blocker

    Purity:

    >95%

    Pack:
    10μg
    Price:
    $156
    Qty:
    Pack:
    100μg
    Price:
    $545
    Qty:
  3. Pack:
    50mg
    Price:
    $45
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    Pack:
    250mg
    Price:
    $77
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    Pack:
    1g
    Price:
    $125
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  4. SOR-C13 (HB9294)

    Description:

    TRPV6 antagonist

    Pack:
    1mg
    Price:
    $246
    Qty:
  5. SP600125 (HB2234)

    Description:

    Selective, ATP-competitive JNK inhibitor. Prevents BMP9-induced osteogenic MSC differentiation. Maintains stem cells in naive pluripotent state.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    Qty:
    Pack:
    50mg
    Price:
    $310
    Qty:
  6. Spadin (HB5438)

    Description:

    Potent TREK-1/ K2P2.1 channel blocker. Shows fast-acting antidepressant effects.

    Pack:
    1mg
    Price:
    $127
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  7. Pack:
    50mg
    Price:
    $133
    Qty:
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