Product overview

Name SOR-C13
Biological description

High affinity, use-dependent hTRPV6 antagonist (IC50 =14nM). SOR-C13 is a carboxy terminal truncated peptide derived from soricidin, a 54 residue paralytic peptide found in Blarina brevicauda venom. It reduces growth of human ovarian xenografts in vivo in NOD/SCID mouse models.

Purity >95%
Description

TRPV6 antagonist

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Solubility & Handling

Storage instructions -20°C
Solubility overview

Soluble in aqueous buffer

Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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Dilution

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Chemical Data

Purity >95%
Molecular Weight 1565.81
Molecular Formula C72H116N20O19
Sequence (one letter) KEFLHPSKVDLPR
Sequence (three letter) H-Lys-Glu-Phe-Leu-His-Pro-Ser-Lys-Val-Asp-Leu-Pro-Arg-OH
CAS Number 1187852-48-7
PubChem identifier 121596688
InChiKey LGANPTNILMNMES-TVNHODDRSA-N

References for SOR-C13

References are publications that support the biological activity of the product
  • Inhibition of Transient Receptor Potential Vanilloid 6 channel, elevated in human ovarian cancers, reduces tumour growth in a xenograft model.

    Xue H et al (2018) Journal of Cancer 9 : 3196-3207
  • In vivo detection of human TRPV6-rich tumors with anti-cancer peptides derived from soricidin.

    Bowen CV et al (2013) PloS one 8 : e58866

2 Item(s)