Target

Potent endothelin receptor antagonist

Selective 5-HT₂ receptor antagonist

Immediate precursor of dopamine

Potent EGFR tyrosine kinase inhibitor

Potent, selective ALK2/ALK3 inhibitor which also promotes neural induction of hPSCs. May be used as a component for brain organoid production.

Potent and selective ACKR3 (CXCR7) agonist. Potentiates opioid peptide activity.

Potent, selective µ-opioid receptor agonist

Selective, non-peptide AT₁ antagonist

Selective I₂-imidazoline receptor ligand

Novel, potent covalent A_2A antagonist. Binds irreversibly.