Kendomycin

(HB3950)

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Product overview

Name Kendomycin
Purity >98%
Description Potent endothelin receptor antagonist
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Biological Data

Biological description Antibiotic. Potent endothelin receptor antagonist. Anti-osteoporotic. Antibacterial Cytotoxic. Mediates its cytotoxic effects, at least in part, through proteasome inhibition.

Solubility & Handling

Solubility overview Slightly soluble in methanol or DMSO
Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Purity >98%
Chemical name (1R,9R,10S,12S,14E,16S,19R,20R,21S,22R)-3,9,21-trihydroxy-6,10,12,14,16,20,22-heptamethyl-23,24-dioxatetracyclo[17.3.1.17,9.02,8]tetracosa-2,5,7,14-tetraen-4-one
Molecular Weight 486.6
Chemical structure Kendomycin [183202-73-5] Chemical Structure
Molecular Formula C29H42O6
CAS Number 183202-73-5
SMILES [H][C@]12CC[C@H](C)\C=C(C)\C[C@@H](C)C[C@H](C)[C@]3(O)OC4=C(C)C(=O)C(O)=C(C4=C3)[C@]([H])(O1)[C@H](C)[C@@H](O)[C@H]2C
Source Isolated from Streptomyces violaceoruber
InChiKey HKLDUJXJTQJSEJ-OLXNOMCWSA-N
Appearance Yellow powder