Selective 5-HT2 serotonin receptor antagonist. Shows dose-dependent α-1 adrenoceptor inhibition. Used to differentiate between 5-HT1D subtypes by showing selectivity for 5-HT1Dα. Shows antihypertensive, antidepressant and anti-leishmaniasis actions.
Solubility & Handling
Storage instructions
Room temperature
Solubility overview
DMSO (100mM) and Water (10mM)
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References are publications that support the biological activity of the product
Ketanserin, an antidepressant, exerts its antileishmanial action via inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) enzyme of Leishmania donovani.
Singh S et al (2014) Parasitol Res 113(6) : 2161-8.