Selective 5-HT2 serotonin receptor antagonist. Shows dose-dependent α-1 adrenoceptor inhibition. Used to differentiate between 5-HT1D subtypes by showing selectivity for 5-HT1Dα. Shows antihypertensive, antidepressant and anti-leishmaniasis actions.
Solubility & Handling
Solubility overview
DMSO (100mM) and Water (10mM)
Storage instructions
Room temperature
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References are publications that support the biological activity of the product
Ketanserin, an antidepressant, exerts its antileishmanial action via inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) enzyme of Leishmania donovani.
Singh S et al (2014) Parasitol Res 113(6) : 2161-8.
![Ketanserin tartrate [83846-83-7] Chemical Structure](https://cdn.hellobio.com/media/catalog/product//h/b/hb1641.png "Ketanserin tartrate [83846-83-7]")
Understanding purity and quality - a guide for life scientists
