Hedgehog signaling

Potent EGFR tyrosine kinase inhibitor

Potent, selective ALK2/ALK3 inhibitor which also promotes neural induction of hPSCs. May be used as a component for brain organoid production.

Potent and selective ACKR3 (CXCR7) agonist. Potentiates opioid peptide activity.

Potent, selective µ-opioid receptor agonist

Selective, non-peptide AT₁ antagonist

Selective I₂-imidazoline receptor ligand

Novel, potent covalent A_2A antagonist. Binds irreversibly.

Novel, covalent Affinity-Based Probe (AfBP). Clickable antagonist for the A₂AR.

Novel, intracellular covalent chemokine CCR2 negative allosteric modulator (NAM). Binds irreversibly.

Novel, potent, selective A₃AR covalent antagonist