My Cart
My account
Menu
Main Menu

LUF7487

(HB9585)
Be the first to add a publication
Technical documents: Datasheet
Be the first to review this product
Add to Wish List

Product overview

Name LUF7487
Biological description

Novel, covalent Affinity-Based Probe (AfBP) which is suitable for click-conjugation (e.g. with the Cyanine-3 fluorophore) for visualization applications (e.g. SDS-PAGE). Irreversibly binds to the A2AR (apparent pKi values at A2aAR are 8.41 (after 0.5h) and 8.82 (after 3h), where a Ki indicates a covalent mode of action).

Sold under license from the Oncode Institute and Universiteit Leiden

Purity >95%
Description

Novel, covalent Affinity-Based Probe (AfBP). Clickable antagonist for the A2AR.

Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (1)
Write Your Own Review
You're reviewing:LUF7487
Rate this item:

Solubility & Handling

Storage instructions -20°C
Solubility overview Soluble in DMSO
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

=
x
x
More Info

Dilution

x
=
x
More Info

Chemical Data

Purity >95%
Chemical name 4-[5-[[7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino]pentyl-prop-2-ynylcarbamoyl]benzenesulfonyl fluoride
Molecular Weight 526.5
Chemical structure Chemical Structure
Molecular Formula C23H23FN8O4S
PubChem identifier 145953622
SMILES C#CCN(CCCCCNC1=NC2=NC(=NN2C(=N1)N)C3=CC=CO3)C(=O)C4=CC=C(C=C4)S(=O)(=O)F
InChiKey KGDQUCQGDCWHAI-UHFFFAOYSA-N
Licensing details

Sold under license from the Oncode Cancer Institute and Universiteit Leiden

References for LUF7487

References are publications that support the biological activity of the product

  • An Affinity-Based Probe for the Human Adenosine A(2A) Receptor.

    Yang X et al (2018) Journal of medicinal chemistry 61 : 7892-7901
    Read more (PubMedID: 30080404)

1 Item

Related Products
Grouped product items
Order: HB9585
Pack PriceQty
50μg
$275

Novel, covalent Affinity-Based Probe (AfBP). Clickable antagonist for the A2AR.

Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

Contact Us

Call 609-683-7500
Fax 609-228-4994

customercare-usa@hellobio.com

New Products in this Area

Pexidartinib (PLX3397)
HB8991

Potent CSF-1R inhibitor. Widely used microglia-depletion agent.

Related Products

ZM 241385
Code:
HB2096
Pack:
10mg, 50mg
Price:
$130, $540
Potent, selective A2A receptor antagonist
CA200645 CellAura fluorescent adenosine A3 antagonist [XAC]
Code:
HB7812
Pack:
50μg
Price:
$275
Fluorescent A3 adenosine receptor antagonist
LUF7445
Code:
HB8439
Pack:
50μg
Price:
$275
Novel, potent covalent A2A antagonist. Binds irreversibly.