Hedgehog signaling

Mitosis inhibitor, widely used as a cell cycle synchronizing agent. Enhances HDR efficiency and increases Cas9-mediated gene editing frequencies.

Potent, selective nNOS inhibitor

Competitive, selective PKC inhibitor

Potent, selective K_Ca1.1 channel activator

Potent, selective K_Ca1.1 channel activator

K_v11.1 channel activator

Potent, selective K_Ca3.1 / K_Ca2 channel subfamily activator

Potent, selective JAK2 inhibitor

Non-selective HDAC inhibitor

Selective Ub-conjugating enzyme (E2) complex Ubc13-Uev1A inhibitor