Potent and selective nNOS inhibitor (Ki = 50 nM). Highly selective for nNOS over eNOS and iNOS. Shows anti-convulsant actions and decreases blood pressure.
Solubility & Handling
Solubility overview
Soluble in water (100mM) or DMSO (100nM)
Storage instructions
room temperature (desiccate)
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References are publications that support the biological activity of the product
N(w) -propyl-L-arginine (L-NPA) reduces status epilepticus and early epileptogenic events in a mouse model of epilepsy: behavioural, EEG and immunohistochemical analyses.
Beamer E et al (2012) Eur J Neurosci 36(9) : 3194-203.