Organoids

Organoids are 3D tissue/organ models made up of pluripotent stem cells and other supporting co-cultured cells eg. epithelial cells. Many types of organoids have been developed to date, including brain, pancreas, heart, lung, intestine, liver, optic cup and cancer organoids. They make stable model systems and can be derived from human stem cells or from patient derived iPSCs. Small molecules are increasingly being used to grow and maintain organoids because of their ease of use and controllable quality, enabling consistent, repeatable results. Researchers can save up to 50% on high purity small molecules used to generate organoids – the range from Hello Bio is around half the price of other suppliers.

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  1. Rapamycin (HB2779)

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    Description:

    mTOR inhibitor and potent immunosuppressant. Also used in inducible gene editing methods (e.g. CRISPR/Cas9) and promotes hPSC differentiation.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $146
    Free trial
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    Pack:
    5mg
    Price:
    $247
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  2. RWJ 67657 (HB1300)

    Description:

    Potent p38 MAPK inhibitor

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $52
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    Pack:
    5mg
    Price:
    $88
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    Pack:
    10mg
    Price:
    $162
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  3. S14161 (HB4068)

    Description:

    pan Class I PI3K isoforms inhibitor

    Purity:

    >99%

    Pack:
    5mg
    Price:
    $367
    Qty:
  4. SB 202190 (HB1301)

    Description:

    Potent ATP competitive p38 MAPK inhibitor. 3D growth matrix component, promotes long-term organoid growth and can be used in production of gastric organoids. Promotes stability of human pluripotent stem cells.

    Purity:

    >99%

    Pack:
    5mg
    Price:
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    Pack:
    10mg
    Price:
    $137
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    Pack:
    25mg
    Price:
    $339
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    Pack:
    50mg
    Price:
    $570
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  5. SB 203580 (HB1302)

    Description:

    Potent, selective p38 MAPK inhibitor. Stimulates neural stem cell proliferation.

    Purity:

    >98%

    Pack:
    500μg
    Price:
    $47
    Qty:
    Pack:
    1mg
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    Pack:
    10mg
    Price:
    $191
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    Pack:
    50mg
    Price:
    $703
    Qty:
  6. Pack:
    5mg
    Price:
    $58
    Qty:
    Pack:
    10mg
    Price:
    $92
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    Pack:
    25mg
    Price:
    $188
    Qty:
  7. Pack:
    1mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $170
    Qty:
    Pack:
    50mg
    Price:
    $719
    Qty:
  8. SP600125 (HB2234)

    Description:

    Selective, ATP-competitive JNK inhibitor. Prevents BMP9-induced osteogenic MSC differentiation. Maintains stem cells in naive pluripotent state.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    Qty:
    Pack:
    50mg
    Price:
    $323
    Qty:
  9. Stattic (HB1437)

    Description:

    Selective STAT3 inhibitor

    Purity:

    >99%

    Pack:
    5mg
    Price:
    $65
    Qty:
    Pack:
    25mg
    Price:
    $262
    Qty:
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