Organoids
Organoids are 3D tissue/organ models made up of pluripotent stem cells and other supporting co-cultured cells eg. epithelial cells. Many types of organoids have been developed to date, including brain, pancreas, heart, lung, intestine, liver, optic cup and cancer organoids. They make stable model systems and can be derived from human stem cells or from patient derived iPSCs. Small molecules are increasingly being used to grow and maintain organoids because of their ease of use and controllable quality, enabling consistent, repeatable results. Researchers can save up to 50% on high purity small molecules used to generate organoids – the range from Hello Bio is around half the price of other suppliers.
Trans-ISRIB (HB4567)
Description:Integrated stress response (ISR) inhibitor. Promotes pluripotent stem cell survival as part of the CEPT cocktail.
Purity:>98%
Tranylcypromine hydrochloride (HB1412)
Description:LSD1 / MAO inhibitor. Enables reprogramming of mouse embryonic fibroblasts into iPS cells.
Purity:>98%
Trichostatin A (HB1402)
Description:Potent HDAC inhibitor. Induces hiPSCs differentiation to cardiogenic cells and induces accelerated dedifferentiation of primordial germ cells.
Purity:>98%
Troglitazone (HB2559)
Description:Potent, selective PPARγ agonist. Inhibits hematopoietic cell line growth.
Purity:>97%