Novel, potent and cell permeable TRPM2 antagonist (IC50 = 396nM). Prevents ligand binding and TRPM2 activation. Inhibits over 90% of human TRPM2 channel currents at concentrations as low as 2 μM. Shows neuroprotective effects in animal models of focal and global ischemia. Active in vivo.
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use
Understanding purity and quality - a guide for life scientists
