Stem cells are unspecialized cells that are capable of self-renewal through mitotic cell division. They may be induced to form more specialized cells by a process termed cellular differentiation.The main types of stems cells are embryonic stem cells (ESCs) found in blastocysts; adult (or somatic) stem cells, found in adult tissues, induced pluripotent stem cells (iPSCs) and cancer stem cells (CSCs). Small molecule pharmacological tools can be used to manipulate signalling pathways during the in vitro culture of stem cells. These tools can be used to target signaling pathways that control cell proliferation and differentiation. Researchers can save up to 50% on stem cell research tools from Hello Bio - they are around half the price of other suppliers.
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AMD 3100 octahydrochloride (HB2739)Description:
Potent, selective CXCR4 antagonist. Mobilizes hematopoietic stem cells.
Recombinant human BDNF protein (HB3485)Description:
Member of the neurotrophin growth factor family. Plays an important role in synaptic plasticity and neurogenesis.
Smo and hedgehog (Hh) signaling inhibitor. Also depletes stem like cancer cells and induces hESCs into endocrine cells.Purity:
Anti-inflammatory synthetic glucocorticoid. Induces hMSC differentiation. Apoptosis inducer.Purity:
Dexamethasone (water-soluble) (HB6020)Description:
Synthetic glucocorticoid with potent anti-inflammatory actions. Induces hMSC differentiation. Apoptosis inducer. Water soluble and suitable for cell culture.Purity:
EC 23 (HB2592)Description:
Synthetic retinoid. Induces neural differentiation of hESCs.Purity:
Fluoxetine hydrochloride (HB1600)Description:
Selective 5-HT uptake inhibitor. Affects differentiation of NSCs.Purity: