TLR7

Selective PIEZO1 channel activator

Novel, selective Piezo1 channel activator. Improved efficacy, potency and solubility compared to Yoda1.

Potent 5-HT₃ antagonist and 5-HT₄ agonist. Also selective IK1 channel agonist.

HCN channel blocker. Potent, selective bradycardic agent.

HCN channel blocker. Modulates sino-atrial node function.

Irreversible, selective caspase 3 inhibitor

Cell permeable caspase 3 specific inhibitor

Estrogen receptor agonist

DNA methyltransferase inhibitor. Induces cardiomyocyte differentiation in MSCs.

Apoptosis inducer. Modulates NF-κB activation.