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Inflammasome
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Inflammasomes are an important part of the innate immune system which are activated upon cellular infection or stress to trigger maturation of proinflammatory cytokines. They regulate the activation of caspase-1 and induce an inflammatory response.
Ac-Arg-Leu-Arg-AMC (HB3733)
Description:Fluorogenic tri-peptide substrate. Useful for measuring trypsin-like 20S proteasome peptidase activity.
Purity:>97%
Amastatin hydrochloride (HB3757)
Description:Competitive aminopeptidase (AP) inhibitor
Purity:>98%
Camostat mesylate (HB3595)
Description:Serine protease inhibitor. Inhibits TMPRSS2 and partially blocks SARS-Cov2 entry in vitro.
Purity:>98%
Compound E (HB3849)
Description:Potent, selective, non-competitive γ-secretase inhibitor. Induces neuronal differentiation.
Purity:>98%
DAPT (HB3345)
Description:γ-secretase inhibitor and classical notch inhibitor. Induces neuronal differentiation. 3D Growth matrix component and used in cerebral organoid differentiation media.
Purity:>98%