ROCK (Rho-kinase)

Selective negative allosteric modulator of GluN2B (NR2B) containing NMDARs

Potent, selective PKC inhibitor

Potent, selective PKC inhibitor. GRK inhibitor.

Potent, competitive kynurenine 3-hydroxylase inhibitor

Potent, selective PDE4 inhibitor. Enantiomer of Rolipram.

Selective PDE4 inhibitor

PDE4 inhibitor. Less potent enantiomer of Rolipram.

Selective D₂-like receptor agonist

Potent, selective CDK1 inhibitor

Potent and selective PPARγ agonist. Promotes adipocyte differentiation and enhances NPC proliferation.