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Biological Data
Biological description | (S)-enantiomer of (R)-roscovitine. Potent selective cyclin-dependent kinase 1 (CDK1) inhibitor. Potential neuroprotectant for stroke. Crosses the blood brain barrier. Inhibits CDK5, consequently blocking hypoxia-induced apoptosis in neurons. Potential anti-inflammatory compound. Potential antidiabetic compound. |
Solubility & Handling
Storage instructions | +4°C |
Solubility overview | Soluble in DMSO (100 mg/ml) |
Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
Chemical name | 2-(S)-(1-Ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine |
Chemical structure | |
Molecular Formula | C19H26N6O |
PubChem identifier | 6603989 |
SMILES | CC[C@@H](CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CC=CC=C3 |
InChi | InChI=1S/C19H26N6O/c1-4-15(11-26)22-19-23-17(20-10-14-8-6-5-7-9-14)16-18(24-19)25(12-21-16)13(2)3/h5-9,12-13,15,26H,4,10-11H2,1-3H3,(H2,20,22,23,24)/t15-/m0/s1 |
InChiKey | BTIHMVBBUGXLCJ-HNNXBMFYSA-N |
Appearance | White to off-white solid |
Potent, selective CDK1 inhibitor