Product overview

Name (S)-Roscovitine
Purity >99%
Description Potent, selective CDK1 inhibitor
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Biological Data

Biological description (S)-enantiomer of (R)-roscovitine. Potent selective cyclin-dependent kinase 1 (CDK1) inhibitor. Potential neuroprotectant for stroke. Crosses the blood brain barrier. Inhibits CDK5, consequently blocking hypoxia-induced apoptosis in neurons. Potential anti-inflammatory compound. Potential antidiabetic compound.

Solubility & Handling

Solubility overview

Soluble in DMSO (100 mg/ml)

Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >99%
Chemical name

2-(S)-(1-Ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine

Molecular Weight 354.5
Chemical structure (S)-Roscovitine [186692-45-5] Chemical Structure
Molecular Formula C19H26N6O
CAS Number 186692-45-5
PubChem identifier 6603989
SMILES CC[C@@H](CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CC=CC=C3
InChi InChI=1S/C19H26N6O/c1-4-15(11-26)22-19-23-17(20-10-14-8-6-5-7-9-14)16-18(24-19)25(12-21-16)13(2)3/h5-9,12-13,15,26H,4,10-11H2,1-3H3,(H2,20,22,23,24)/t15-/m0/s1
InChiKey BTIHMVBBUGXLCJ-HNNXBMFYSA-N
Appearance White to off-white solid