Product overview

Name (R,S)-Rolipram
Purity >98%
Description Selective PDE4 inhibitor
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Biological Data

Biological description Selective phosphodiesterase PDE4 inhibitor (IC50 values are ~130 nM and 240 nM for PDE4B and PDE4D respectively). Shows antiinflammatory, antidepressant, neuroprotective effects and actions against Alzheimer's disease.

Solubility & Handling

Solubility overview Soluble in DMSO (75 mM) and ethanol (75 mM)
Storage instructions Room temperature
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >98%
Chemical name 4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one
Molecular Weight 275.35
Molecular Formula C16H21NO3
CAS Number 61413-54-5
PubChem identifier 5092
SMILES COc1ccc(cc1OC2CCCC2)C3CNC(=O)C3